Is resistin the master link between inflammation and inflammation-related chronic diseases?
نویسندگان
چکیده
منابع مشابه
Role of resistin in inflammation and inflammation-related diseases.
Resistin is a newly identified adipocyte secreted hormone belonging to a cysteine-rich protein family. It is expressed in white adipose tissues in rodents and has also been found in several other tissues in human. Insulin, glucose, many cytokines and anti-diabetic thiazolidinediones are regulators of resistin gene expression. Resistin was firstly proposed to be involved in insulin resistance an...
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Adipose tissue secretes a variety of bioactive substances that are associated with chronic inflammation, insulin resistance, and an increased risk of type 2 diabetes mellitus. While resistin was first known as an adipocyte-secreted hormone (adipokine) linked to obesity and insulin resistance in rodents, it is predominantly expressed and secreted by macrophages in humans. Epidemiological and gen...
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ژورنال
عنوان ژورنال: Molecular and Cellular Endocrinology
سال: 2021
ISSN: 0303-7207
DOI: 10.1016/j.mce.2021.111341